PEAK-RC – Participating Exercise Prehabilitation to Keep up Function Capacity for Radical Cystectomy: A Window-of-Opportunity Randomized Controlled Trial

Dr. Yang

The PEAK-RC study is a randomized controlled trial testing the feasibility and preliminary efficacy of a HIIT intervention that prepares bladder cancer patients for radical cystectomy.

RiskDialogue – Making healthy behaviour changes easy: AI-enabled dialogue-driven app for personalized cancer prevention

Dr. Yang

About 40% of cancer cases in Canada could be prevented following CCS recommendations to “make healthy choices” and the creation of health-supporting environments.

The PEAK program – Development, Implementation, and Evaluation of a Cancer Prehabilitation Program to Enhance Knowledge, Improve Mental Health and Keep Up Physical Function

Dr. Yang

“It is a marathon, not a sprint”. The journal of facing cancer is often likened to a marathon rather than a spirit, as it involves challenges that span from diagnosis to long-term survivorship.

PEAK-AS – Exercise intervention for prostate cancer men managed by active surveillance: a knowledge survey

Dr. Yang

Active surveillance has been recommended as the preferred management strategy to avoid or postpone immediate therapy for low-risk (potentially intermediate-risk) prostate cancer…

Nishtohtamihk li kaansyr (Understanding Cancer): Cancer Screening, Outcomes and Experiences among Métis People in Alberta

Dr. Kopciuk

This co-designed study between the Métis Nation of Alberta (AB) and AHS Screening Programs will evaluate cancer screening outcomes and experiences of Métis Albertans…

Adolescents and Young Adults becoming Physically Active after Cancer Trial (AYA-PACT)

Dr. Fidler-Benaoudia and Dr. Friedenreich

The Adolescents and Young Adults becoming Physically Active after Cancer Trial (AYA-PACT) is a randomized controlled exercise intervention…

Cancer incidence: Outdoor air pollution

Dr. Peters and Dr. Yang

Outdoor air pollution is a known lung carcinogen. However, little is known about the relationship between air pollution and other types of cancer…

PEAK-RP – Participating in Tai Chi to Reduce Anxiety and Keep up Physical Function: a Prehabilitation Intervention for Radical Prostatectomy

Dr. Yang

The PEAK-RP study is a randomized controlled trial testing the implementation strategy of a mind-body-exercise intervention that prepares prostate cancer patients and their caregivers for radical prostatectomy…

Shaping up on physical activity and cancer: Improving estimates of cancer risk using accelerometry and contemporary methods in the UK Biobank

Dr. Yang

There are inherent limitations of self-report data associated with measurement error. This project uses novel and innovative methods to estimate the attenuation of the association between self-reported physical activity and cancer risk associated with measurement error…

Late effects of childhood cancer

Dr. Fidler-Benaoudia

Although survival from childhood cancer has increased substantially in the last decades, treatments used to achieve cure are known to cause late effects, or health problems that occur months or years after treatment has ended…

The harms of thyroid cancer overdiagnosis

Dr. Fidler-Benaoudia

The number of people with thyroid cancer has been growing in Canada for more than 30 years due to advances in medical imaging, with people aged 15 to 49 years having the largest increases. Fortunately, most people can beat this disease, so there is a growing number of thyroid cancer survivors in Canada. This leads to many questions …

Alberta Adolescent and Young Adult Cancer Survivor Study

Dr. Fidler-Benaoudia

The Alberta Adolescent and Young Adult Cancer Survivor Study is a population-based, retrospective cohort study that includes all individuals that were diagnosed with cancer between the ages of 15 and 39 years in Alberta from 1983 to 2017. The cohort includes nearly 25,000 adolescent and young adult (AYA) cancer survivors, …

Assessing cancer screening participation and uptake among First Nations people of Alberta

Dr. Kopciuk

Cancer rates in First Nations (FN) people are higher than the general Canadian population for many kinds of cancer, including those that could be prevented or caught early through cancer screening programs. When cancer is detected in FN people, it is often more advanced as well making it more difficult to treat..…

Determinants of cancer stage at diagnosis

Dr. Kopciuk

This project will explore factors associated with early stage of cancer at diagnosis, using data from Alberta’s Tomorrow Project The specific aims are to: (1) develop multivariable regression models using ordinal logistic regression to identify independent and synergistic factors (clinical, lifestyle, screening, etc.) associated with cancer stage at diagnosis; (2) develop spatial regression models to account for geographic and other factors …

The ComPARe Project

Dr. Brenner and Dr. Friedenreich

This project quantified the number and proportion of incident cancer cases in Canada, now and to 2042, that could be prevented through changes in modifiable lifestyle and environmental exposures associated with cancer. The broad risk factor categories of interest were: tobacco exposure, dietary factors, physical inactivity, sedentary behavior, obesity, environmental factors, infectious agents….

The Alberta Moving Beyond Breast Cancer (AMBER) Study

Dr. Friedenreich

The overall aim of this research is to study how physical activity and health-related fitness (e.g. physical fitness and body composition) are associated with survival after breast cancer. The cohort study has enrolled 1528 newly diagnosed breast cancer survivors in Alberta since 2012 and is following up these participants with regular assessments …

Breast Cancer to Bone (B2B) Metastases Research Program

Dr. Kopciuk

The B2B research program established a cohort newly diagnosed breast cancer cases with the objective of studying how breast cancer metastasizes to the bone. This cohort study has involved several sub-projects including one currently led by Dr. Kopciuk to investigate the impact of vitamin D and markers of inflammation in breast cancer metastases. Other projects…

The Breast Cancer and Exercise Trial in Alberta (BETA Trial)

Dr. Friedenreich

The Breast Cancer and Exercise Trial in Alberta (BETA) was a randomized controlled exercise intervention trial. Dr. Friedenreich and her colleagues recruited 400 postmenopausal women aged 50-74 years of age to examine how a one-year high volume (300 minutes per week) versus moderate volume (150 minutes per week) aerobic exercise intervention influences and modifies biomarkers for breast cancer risk …


Dr. Friedenreich

The Colon Health and Life Long Exercise Trial (CHALLENGE Trial) is a multi-centre randomized controlled exercise intervention trial that is funded and coordinated by the Cancer Clinical Trials Group at Queen’s University, Kingston. Dr. Friedenreich is a co-investigator on this first ever trial that is enrolling and randomizing 962 Stage II and III colon cancer…

The Endometrial Cancer Cohort Study

Dr. Friedenreich

The Endometrial Cancer Cohort study includes 540 incident cases of endometrial cancer that were diagnosed in Alberta between 2001-2006 who were initially part of a population-based case-control study of lifetime physical activity and endometrial cancer risk that we conducted that also included about 1000 controls. The cases were interviewed after…

The Prostate Cohort Study

Dr. Friedenreich

The Prostate Cancer Cohort Study includes nearly 1000 incident cases of prostate cancer who were diagnosed between 1997-2000 in Alberta and were part of a population-based case-control study that we conducted here. The cases were initially interviewed at the time of their diagnosis and then re-interviewed approximately two years after diagnosis.…

The Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial

Dr. Friedenreich

The largest study of its kind conducted worldwide, and the first ever in Canada, the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial was a randomized controlled trial designed to examine how a one-year intervention of moderate-to vigorous-intensity exercise (45-minute sessions, 5 days per week) influences several intermediate endpoints for breast cancer …