The ComPARe Project

Dr. Brenner and Dr. Friedenreich

This project is quantifying the number and proportion of incident cancer cases in Canada, now and to 2042, that could be prevented through changes in modifiable lifestyle and environmental exposures associated with cancer. The broad risk factor categories of interest are: tobacco exposure, dietary factors, physical activity, obesity, environmental factors, infectious diseases and hormonal therapies…

The Alberta Moving Beyond Breast Cancer (AMBER) Study

Dr. Friedenreich

The overall aim of this research is to study physical activity and health-related fitness (e.g. physical fitness and body composition) in order to improve the quality of life for breast cancer survivors. The study will enroll 1500 newly diagnosed breast cancer survivors in Alberta over a 5 year period. Health status will be measured at baseline…

Breast Cancer to Bone (B2B) Metastases Research Program

Dr. Kopciuk and Dr. Friedenreich

The B2B research program established a cohort newly diagnosed breast cancer cases with the objective of studying how breast cancer metastasizes to the bone. This cohort study has involved several sub-projects including one currently led by Dr. Kopciuk to investigate the impact of vitamin D and markers of inflammation in breast cancer metastases. Other projects…

The Breast Cancer and Exercise Trial in Alberta (BETA Trial)

Dr. Friedenreich

The Breast Cancer and Exercise Trial in Alberta (BETA) is a randomized controlled exercise intervention trial. Dr. Friedenreich and her colleagues recruited 400 postmenopausal women aged 50-74 years of age to examine how a one-year high volume (300 minutes per week) versus moderate volume (150 minutes per week) aerobic exercise intervention influences and modifies biomarkers for breast cancer risk …

The CHALLENGE Trial

Dr. Friedenreich

The Colon Health and Life Long Exercise Trial (CHALLENGE Trial) is a multi-centre randomized controlled exercise intervention trial that is funded and coordinated by the Cancer Clinical Trials Group at Queen’s University, Kingston. Dr. Friedenreich is a co-investigator on this first ever trial that is enrolling and randomizing 962 Stage II and III colon cancer…

The Endometrial Cancer Cohort Study

Dr. Friedenreich

The Endometrial Cancer Cohort study includes 540 incident cases of endometrial cancer that were diagnosed in Alberta between 2001-2006 who were initially part of a population-based case-control study of lifetime physical activity and endometrial cancer risk that we conducted that also included about 1000 controls. The cases were interviewed after their diagnoses, and again about…

The Prostate Cohort Study

Dr. Friedenreich

The Prostate Cancer Cohort Study includes nearly 1000 incident cases of prostate cancer who were diagnosed between 1997-2000 in Alberta and were part of a population-based case-control study that we conducted here. The cases were initially interviewed at the time of their diagnosis and then re-interviewed approximately two years after diagnosis. They were also asked…

The Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial

Dr. Friedenreich

The largest study of its kind conducted worldwide, and the first ever in Canada, the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial was a randomized controlled trial designed to examine how a one-year intervention of moderate-to vigorous-intensity exercise (45-minute sessions, 5 days per week) influences several intermediate endpoints for breast cancer …