Nigel Brockton & Joseph Roberts
Biospecimens as Observational Data: How Does What You Collect and Who You Collect it from Impact the Validity of the Downstream Research?
This presentation will highlight critical differences between observational and experimental data and how the intrinsic observational nature of human biospecimens should influence the activities of biobanks. The logistics of biospecimen collection can introduce selection bias into downstream research if unbalanced selection is not addressed. However, few biobanks are equipped to provide source population metrics with distributed biospecimens and few biospecimen recipients request such data.
Biobanks operators must be the agents of change who promote the application of population metrics to mitigate the potential impact of selection bias in downstream research. This presentation will hopefully convince the audience that population metrics are an essential component of biospecimen quality.
1. To understand how non-random participant selection/ biospecimen collection can impact downstream research
2. To help participants identify potential selection concerns within their own or existing biobanks
3. To review methods to eliminate or mitigate the impact of non-random participant selection
Emphasize the role of biobanks in promoting the strengths and limitations of biospecimens as observational data.
Pretest Time: Start: 10:45 End: 11:00 MST/MDT
*Audio 11 – 1 (866) 236-8306; Part Code 1043403 (Bridge line for those of you who wish to call in)
*CAL – Holy Cross – Rm G020A/B
CAL – Richmond Road Diagnostic Treatment Centre – Rm 3005
CAL – Tom Baker – Rm AE173U Desktop
EDM – Kingsway Garden Mall – Rm 311 (Screen Test)
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UofA – ECHA #1