The B2B research program established a cohort newly diagnosed breast cancer cases with the objective of studying how breast cancer metastasizes to the bone. This cohort study has involved several sub-projects include one currently led by Dr Kopciuk to investigate the impact of vitamin D and markers of inflammation in breast cancer metastases. Other projects are examining the detection of metabolomic profiles indicative of bone metastases or metastatic potential and the contribution of breast cancer stem cells to metastatic bone disease.
Co-Principal Investigators: Dr. Friedenreich and Dr Brockton (currently at the American Institute of Cancer Research)
Co-investigators: Dr Linda Cook, Dr Carrie Shemanko, Dr Hans Vogel, Dr David Hanley, Dr Alexander Paterson
Funder: Alberta Cancer Foundation