Dr. Brenner and Dr. Friedenreich
This project quantified the number and proportion of incident cancer cases in Canada, now and to 2042, that could be prevented through changes in modifiable lifestyle and environmental exposures associated with cancer. The broad risk factor categories of interest were: tobacco exposure, dietary factors, physical inactivity, sedentary behavior, obesity, environmental factors, infectious agents. This project included a Pan-Canadian group of co-investigators as well as major partnership with the Canadian Cancer Society. A committee of knowledge end-users for this research is also participating in this project. Several papers were published in a Special Issue of Preventive Medicine in 2019 and a dedicated website and data dashboard are also available at https://prevent.cancer.ca/.
A follow-up of the ComPARe project using the OncoSim model in conjunction with the Canadian Partnership Against Cancer has been conducted to estimate the impact on cancer mortality through changes in these cancer risk factors. The health economic impact of these changes has also been estimated and publications are under review.
Co-Principal Investigator(s): Dr. Darren Brenner and Dr. Christine Friedenreich
Co-investigators: Dr. Eduardo Franco, Dr. Will King, Dr. Paul Villeneuve, Dr. Paul Demers, Dr. Stephen Walter, Dr. Perry Hystad, Dr. Prithwish De, Dr. Robert Nuttall, Dr. Leah Smith.
Funder: Canadian Cancer Society